Tag Archives: Johns Hopkins

Promising Preclinical Results in Pancreatic Cancer

A recent announcement at the AACRs-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held Oct. 19–23, points to some promising results in recent trials that targeted multiple pathways downstream of KRAS (including PI3K/AKT, RAF/MEK/ERK and RAL).  The studies conducted … Continue reading

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ClinVar – A database of mutations and their clinical relevance

One of the key pieces of the drug discovery puzzle involves determining the clinical relevance of the target.  Over the past few years big pharma have been pulling back from this critical part of the drug discovery process and ceding … Continue reading

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Latest Pancreatic Cancer News & Papers

News In this weeks news: Low oxygen levels could drive cancer growth, research suggests Mutant Kras drives pancreatic cancer maintenance via metabolic pathways Genomics In The Journals | GenomeWeb Daily News | GenomeWeb CytRx Initiates Phase 2 Clinical Trial with … Continue reading

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Latest Pancreatic Cancer Genomics Papers

In The News From the Sol Goldman Pancreatic Cancer Research Institute at Johns Hopkins, a paper recently published in Cancer Discovery points to the ATM (ataxia telangiectasia mutated) gene predisposing certain families to pancreatic cancer. Recent Publications Here are the some of latest … Continue reading

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