Tag Archives: Drug Discovery

Cui Bono? Finding Super Responders In Clinical Trials

I’m a voracious reader of mysteries in my spare time.  And some juncture in every story, as the detective finds himself staring at the corpse, they ask the inevitable question “Cui Bono — who benefits?”  Oddly enough, this is a … Continue reading

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ClinVar – A database of mutations and their clinical relevance

One of the key pieces of the drug discovery puzzle involves determining the clinical relevance of the target.  Over the past few years big pharma have been pulling back from this critical part of the drug discovery process and ceding … Continue reading

Posted in Bioinformatics, Drug Development, Informatics, pancreatic cancer | Tagged , , , , | 2 Comments

Stunning News In Pancreatic Cancer Research

When Gleevec, the very first targeted therapeutic came out, there was a mad rush in the pharmaceutical industry to mine the genome for potential “magic bullet” targets.  In Gleevec’s case, it was able to inhibit the BCR-ABL fusion kinase, and … Continue reading

Posted in Cancer Research, Drug Development, pancreatic cancer, Science Blogging, Uncategorized | Tagged , , , | Leave a comment

The Semantic Web and Drug Discovery

The Semantic Web and Drug Discovery was a recent topic at the San Diego Informatics Lunch forum.  This is an informal get-together of bioinformatics and cheminformatics practitioners to share ideas and discuss how different technologies can be applied in our … Continue reading

Posted in Bioinformatics, Drug Development, Informatics, Semantic Web | Tagged , | 1 Comment