Category Archives: Cancer Research

The Genetics of Pancreatic Cancer

In the second part of this series on pancreatic cancer, we’ll look at the changes in our understanding of the role of familial genetics in pancreatic cancer, and how that new understanding holds promise for new therapeutics. In the mid-1970s … Continue reading

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 Remember, Remember…

A look at our changing understanding of the genetics of pancreatic cancer, and the genomic technologies that helped us gain that understanding over the past 21 years. Continue reading

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Drug Target Identification: And then a miracle occurs

At the front end of most drug discovery programs lies a step called Target Identification, and a few months ago I sat down with a colleague to discuss their approach to target identification.  In particular, “how do you characterize a target”? … Continue reading

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Network of BioThings Hackathon #2

This weekend’s Network of BioThings hackathon (#hackNoB) was a great success with some really innovative projects making great strides in a short amount of time. The event was hosted by the Jeff Grethe of the Neuroscience Information Framework group at … Continue reading

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Network of BioThings: Making PDFs Useful

Recently, Andrew Su of Scripps posted a series of blog entries on the Network of Biothings (NoB) efforts, especially their efforts to uncover use cases that could aid medical research. In a nutshell,”The Network of BioThings aims to structure the … Continue reading

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Tinkering With Semantic Markup

One of the key challenges for bioinformaticians in this age is extracting meaningful findings from abstracts and full text articles. Text mining solutions can only take it so far, and previous comparative studies have shown that Amazon Mechanical Turk solutions and … Continue reading

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Assessing Credibility in Scientific Research

Over the past few years, pharmaceutical companies have come to increasingly rely external research to help fill their pipelines.  This greater reliance on academic research is not without it’s risks — chief amongst these is the lack of reproducibility. Amgen … Continue reading

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