Category Archives: Drug Development

ClinVar – A database of mutations and their clinical relevance

One of the key pieces of the drug discovery puzzle involves determining the clinical relevance of the target.  Over the past few years big pharma have been pulling back from this critical part of the drug discovery process and ceding … Continue reading

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Latest Pancreatic Cancer Articles

During the recent ASCO GI conference, the big news was the release of the results of the Abraxane trials.  The data show that the lives of pancreatic cancer patients can be extended by two months when adding Abraxane into the … Continue reading

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Latest Pancreatic Cancer News & Articles

News In this weeks news: ABRAXANE Demonstrates Statistically Significant Improvement in Overall Survival for Patients with Advanced Pancreatic Cancer in Phase III Study – Yahoo! Finance MONTPELLIER, France: Skuldtech and AB Science Announce the Identification of New Predictive Markers for … Continue reading

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Pancreatic Cancer News & Journal Articles

News In this week’s news includes stories about a viral therapy for pancreatic cancer undergoing preclinical development, the use of a drug to penetrate the stroma surrounding pancreatic cancer tumors at the Fred Hutchinson Institute.  You may remember this approach … Continue reading

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Latest Pancreatic Cancer News & Papers

In answer to the perennial question, “why is there no cure for cancer”, Ed Yong from Discover Magazine discusses the complexity of the tumor microenvironment and why this makes finding new therapeutics especially challenging. News In this weeks news: Mouse … Continue reading

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Pancreatic Cancer Research News and Journal Articles

News In this weeks news: Peregrine’s cancer drug data disappoints; shares plunge | Reuters Peregrine Pharmaceuticals (PPHM.O) said an independent assessment of data from a mid-stage trial showed unexpectedly high progression-free survival rates in lung cancer patients receiving standard chemotherapy, … Continue reading

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AACR Videos on YouTube

Earlier this month, the AACR held it’s Molecular Targets meeting.  The interviews from the meeting are available on YouTube, and you can subscribe to the channel.  Here’s an interesting interview with Dr. Nadia Harbeck with some interesting news about some … Continue reading

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New Pancreatic Cancer Drug Trials

Along with a resurgence in interest from the research and drug discovery communities in pancreatic cancer, there’s been a concomitant increase in the number of drug trials over the past couple of years. Last year, Concordia Pharmaceuticals released the results … Continue reading

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Pancreatic Cancer Genomics Group

In previous blog postings, I’ve mentioned the fact that I’m a fan of the Mendeley website.  It’s a great tool to let scientists share papers that are considered significant to a particular area of study.  In my case, I’m interested … Continue reading

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The Semantic Web and Drug Discovery

The Semantic Web and Drug Discovery was a recent topic at the San Diego Informatics Lunch forum.  This is an informal get-together of bioinformatics and cheminformatics practitioners to share ideas and discuss how different technologies can be applied in our … Continue reading

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